Synthesis and Antitumor Activity of Polyphosphoramides and Polyphosphates Containing Amino Acid,5-Fluorouracil and Nitrogen Mustard
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Graphical Abstract
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Abstract
By the polycondensation of amino acid 5--fluorouracil--1,3--dipropyl esters withbis (2--chloroethyl)--phosphoramidic dichloride in the presence of Et_3N orin Vacuo, tennew polymers containing 5--fluorouracil, nitrogen mustard and amino acid weresynthesize
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