Advances in Construction Strategies of Low-Complication Medical Coatings

The functionality of medical materials is mainly exhibited by the contact between the surface of the medical material and the biological environment. It is necessary to functionalize the surface of the medical material. Otherwise, complications such as bacteria-induced infection and blood clot-induced thrombosis may occur during the implantation/intervention process. This leads to shortened service life and application failure. Based on the above problems, controlling structural composition, constructing functional surfaces, achieving low complications and biocompatibility on the surface of materials have always been important scientific problems that need to be solved in this field. At present, the construction methods of low-complication medical coating mainly include surface chemical graft modification, monolayer self-assembly, layer by layer assembly, dopamine coating, etc. Combined with the research group's low-complication medical polymer materials and medical treatment in recent years, the research results of medical coatings of instruments have briefly introduced the research progress of the surface construction of medical coatings at home and abroad.