Abstract:
Polycations exhibit great potential application in the fields of anti-infection, especially in combating drug-resistant bacteria and breaking through the barrier of biofilm. To enhance the interaction between the prepared polymers and bacteria and the bacterial killing efficacy, a series of biocompatible polycations with excellent performance have been designed and constructed. In this review, the recent progresses in design, preparation, and the application of functional cationic antimicrobial polymers are summarized, and the antimalarial mechanism and the unique properties are discussed. Finally, the current challenges and future perspectives in cationic antimicrobial polymers are put forward.