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    朱欣怡, 丁圣刚, 聂 旋, 尤业字. 抗菌阳离子聚合物的研究进展[J]. 功能高分子学报,2023,36(3):221-239. doi: 10.14133/j.cnki.1008-9357.20221128001
    引用本文: 朱欣怡, 丁圣刚, 聂 旋, 尤业字. 抗菌阳离子聚合物的研究进展[J]. 功能高分子学报,2023,36(3):221-239. doi: 10.14133/j.cnki.1008-9357.20221128001
    ZHU Xinyi, DING Shenggang, NIE Xuan, YOU Yezi. Progress of Antibacterial Polycation[J]. Journal of Functional Polymers, 2023, 36(3): 221-239. doi: 10.14133/j.cnki.1008-9357.20221128001
    Citation: ZHU Xinyi, DING Shenggang, NIE Xuan, YOU Yezi. Progress of Antibacterial Polycation[J]. Journal of Functional Polymers, 2023, 36(3): 221-239. doi: 10.14133/j.cnki.1008-9357.20221128001

    抗菌阳离子聚合物的研究进展

    Progress of Antibacterial Polycation

    • 摘要: 两亲性阳离子聚合物在抗细菌感染,尤其是抵抗细菌耐药、突破细菌生物膜障碍中发挥着重要作用。为了进一步增加阳离子聚合物与细菌等病原体的相互作用,在提高杀菌效率的同时提高生物相容性,研究者们设计与制备了一系列具有优良性能的阳离子聚合物。本文综述了近年来新型阳离子聚合物的设计、制备及其在抗病原体方面的应用,讨论了不同阳离子聚合物的作用机理与特点,并对该领域所面临的挑战进行了展望。

       

      Abstract: Polycations exhibit great potential application in the fields of anti-infection, especially in combating drug-resistant bacteria and breaking through the barrier of biofilm. To enhance the interaction between the prepared polymers and bacteria and the bacterial killing efficacy, a series of biocompatible polycations with excellent performance have been designed and constructed. In this review, the recent progresses in design, preparation, and the application of functional cationic antimicrobial polymers are summarized, and the antimalarial mechanism and the unique properties are discussed. Finally, the current challenges and future perspectives in cationic antimicrobial polymers are put forward.

       

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