基于天然植物骨架构建各向异性水凝胶

袁浩田; 金鑫; 姚远; 林绍梁; 朱新远

doi:10.14133/j.cnki.1008-9357.20210527002

基于天然植物骨架构建各向异性水凝胶

doi: 10.14133/j.cnki.1008-9357.20210527002

1.
上海交通大学化学化工学院, 上海 200240
2.
华东理工大学材料科学与工程学院, 上海 200237

基金项目: 上海市重大基础研究（18JC1410800）；国家自然科学基金（51873106）

详细信息

作者简介:
袁浩田（1995—），男，硕士生，主要研究方向为各向异性水凝胶材料

通讯作者:
金　鑫， E-mail：jxcindy@sjtu.edu.cn

中图分类号: O63
计量
- 文章访问数: 126
- HTML全文浏览量: 77
- PDF下载量: 86
- 被引次数: 0
出版历程
- 收稿日期: 2021-05-27
- 网络出版日期: 2021-11-02

Construction of Anisotropic Hydrogel Based on Natural Plant Skeleton

1.
School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
2.
School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China

摘要

摘要: 各向异性水凝胶因其有序、取向结构而表现出优异的功能性，在仿生肌肉、致动器、药物递送、柔性传感等领域具有极大的应用前景，然而，各向异性水凝胶的制备方法有待丰富和拓展。提出了基于植物骨架构建各向异性水凝胶的新思路：首先，利用光学显微镜、扫描电镜和低场核磁等表征方法，筛选蔬菜组织中各项异性的结构，确定胡萝卜芯为天然结构模板；接着，在天然骨架中引发聚丙烯酰胺水凝胶的原位聚合，以胡萝卜骨架为模板复合水凝胶，制得各向异性水凝胶；最后，结合扫描电镜和力学性能表征发现，以天然取向结构为模板能够简便地制备各向异性水凝胶，且该水凝胶在拉伸强度、断裂伸长率和压缩强度上均表现出显著的力学各向异性。
- 水凝胶 /
- 各向异性 /
- 天然植物 /
- 骨架
Abstract: Biological tissues including muscles, cartilage and other human tissues have excellent mechanical anisotropy and electrical anisotropy due to their reasonable arrangement of microstructures. The anisotropic hydrogel has excellent function due to its ordered orientation structure, which shows great application prospects in biomimetic muscles, actuators, drug delivery, and flexible sensing. However, the methods to prepare anisotropic hydrogels are limited. Inspired by the anisotropic structure from nature products, we proposed a strategy to build anisotropic hydrogel based on plant skeleton. First, we observed and searched for anisotropic structures among diverse vegetables, and pre-treated them to obtain anisotropic skeleton. Furthermore, the cross-linking of polyacrylamide (PAM) within the anisotropic skeleton was in-situ initiated, resulting in a hybrid anisotropic hydrogel. The anisotropic hydrogel with plant skeleton and PAM hydrogel could be successfully constructed. A highly anisotropy in structure and mechanical property could be achieved. This work obtained a highly anisotropic hydrogel with a feasible method, and we hoped to shed new lights for a novel anisotropic hydrogel construction.
- hydrogel /
- anisotropy /
- natural plant /
- skeleton

HTML全文

图 1 利用胡萝卜、芹菜构筑各向异性水凝胶的示意图

Figure 1. Schematic diagram of the construction of anisotropic hydrogels using carrots and celeries

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图 2 胡萝卜样品的（a,b）光学显微镜细胞形态和（c,d）扫描电镜下的结构形貌

Figure 2. （a,b） Cell observation images under optical microscopes and （c,d） scanning electron micrographs of carrot samples

a,c— Vertical growth direction; b,d—Parallel growth direction

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图 3 芹菜样品的（a,b）光学显微镜细胞形态和（c,d）扫描电镜下的结构形貌

a,c— Vertical growth direction; b,d—Parallel growth direction

Figure 3. （a,b） Cell observation images under optical microscopes and （c,d） scanning electron micrographs of celery samples

下载: 全尺寸图片幻灯片

图 4 茄子、杏鲍菇和莴笋样品（a,b,c）在光学显微镜下的细胞形态和（d,e,f）扫描电镜下的结构形貌

Figure 4. （a,b,c） Cell observation images under optical microscopes and （d,e,f） scanning electron micrographs of eggplant, pleurotus eryngii and lettuce samples

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图 5 茄子、胡萝卜、芹菜、莴笋、杏鲍菇样品的低场核磁成像

Figure 5. Low-field NMR imaging of eggplant, carrot, celery, lettuce, and pleurotus eryngii samples

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图 6 胡萝卜、PAM水凝胶和胡萝卜复合PAM水凝胶的红外光谱

Figure 6. FT-IR spectra of carrot, PAM hydrogel and carrot gel

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图 7 （a，b）胡萝卜骨架和（c，d）胡萝卜复合PAM水凝胶的扫描电镜图

a,c— Vertical growth direction; b,d—Parallel growth direction

Figure 7. Scanning electron micrograph of （a，b）carrot skeleton and （c，d） carrot gel

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图 8 （a）胡萝卜复合 PAM水凝胶，（b）PAM 水凝胶，（c）胡萝卜骨架的拉伸应力-应变曲线（L、R分别表示平行、垂直于生长方向）

Figure 8. Tensile stress-strain curves of （a） carrot gel, （b） PAM hydrogel and （c） carrot （ L and R stand for parallel and vertical directions, respectively）

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图 9 PAM水凝胶、胡萝卜复合PAM水凝胶的压缩应力-应变曲线（L、R分别表示平行、垂直于生长方向）

Figure 9. Compression stress-strain curves of PAM hydrogel and carrot gel （L and R stand for parallel and vertical directions, respectively）

下载: 全尺寸图片幻灯片

表 1 各向异性植物水凝胶的构建条件对比

Table 1. Comparison of construction conditions for obtaining the anisotropic hydrogels

w（AM）	m（MBA）/m（AM）	T/ °C	t/ h	Results
20%	0.5%	25	24	Hydrogel forming
20%	0.5%	45	2	Hydrogel forming
20%	0.5%	60	2	Natural skeleton destroyed
25%	0.5%	25	24	Hydrogel forming
25%	0.5%	45	2	Hydrogel forming
25%	0.5%	60	2	Natural skeleton destroyed
30%	0.5%	25	24	Hydrogel forming
30%	0.5%	45	2	Implosion
30%	0.5%	60	2	Natural skeleton destroyed
40%	0.5%	25	24	Hydrogel with bubbles
40%	0.5%	45	2	Hydrogel with bubbles
40%	0.5%	60	2	Implosion

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