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PDA-TiO2杂化纳米粒子的制备及其防晒应用

黎赛瑶 汪洋 李婷 东为富

黎赛瑶, 汪洋, 李婷, 东为富. PDA-TiO2杂化纳米粒子的制备及其防晒应用[J]. 功能高分子学报. doi: 10.14133/j.cnki.1008-9357.20210104001
引用本文: 黎赛瑶, 汪洋, 李婷, 东为富. PDA-TiO2杂化纳米粒子的制备及其防晒应用[J]. 功能高分子学报. doi: 10.14133/j.cnki.1008-9357.20210104001
LI Saiyao, WANG Yang, LI Ting, DONG Weifu. Preparation of PDA-TiO2 Hybrid Nanoparticles and Their Application in Sun Protection[J]. Journal of Functional Polymers. doi: 10.14133/j.cnki.1008-9357.20210104001
Citation: LI Saiyao, WANG Yang, LI Ting, DONG Weifu. Preparation of PDA-TiO2 Hybrid Nanoparticles and Their Application in Sun Protection[J]. Journal of Functional Polymers. doi: 10.14133/j.cnki.1008-9357.20210104001

PDA-TiO2杂化纳米粒子的制备及其防晒应用

doi: 10.14133/j.cnki.1008-9357.20210104001
基金项目: 国家自然科学基金(21975108)
详细信息
    作者简介:

    黎赛瑶(1994—),女,硕士研究生,主要研究方向为复合纳米粒子的紫外屏蔽性。E-mail:18230306627@163.com

    通讯作者:

    东为富,E-mail:wfdong@jiangnan.edu.cn

  • 中图分类号: O63

Preparation of PDA-TiO2 Hybrid Nanoparticles and Their Application in Sun Protection

  • 摘要: 采用溶胶凝胶法制备二氧化钛(TiO2)前驱体,将其与盐酸多巴胺共混后制备聚多巴胺-TiO2(PDA-TiO2)杂化纳米粒子。在PDA与TiO2的协同作用下,PDA-TiO2粒子具有高效的防紫外线性能。利用红外光谱、X射线光电子能谱、扫描电镜、透射电镜、紫外-可见光吸收光谱、热失重曲线以及皮肤渗透实验对纳米粒子的基本结构与性能进行了一系列表征。结果表明:以PDA-TiO2杂化纳米粒子作为唯一功效成分制备的防晒霜,其防晒系数(SPF)达到33.7;PDA具有良好的生物黏附性,能有效防止PDA-TiO2杂化纳米粒子渗透皮肤,确保了其使用安全性。

     

  • 图  1  样品的红外光谱图

    Figure  1.  FT-IR spectra of samples

    图  2  TiO2和PDA-TiO2杂化纳米粒子的XPS谱图

    Figure  2.  XPS spectra of TiO2 and PDA-TiO2 hybrid nanoparticles

    图  3  样品的SEM(a, b, c)和TEM(d, e, f)图

    Figure  3.  SEM (a, b, c) and TEM (d, e, f) images of samples

    图  4  PDA和PDA-TiO2的紫外-可见光吸收谱图

    Figure  4.  UV-Vis absorption spectra of PDA and PDA-TiO2

    图  5  PDA-TiO2的热失重曲线

    Figure  5.  TGA curves of PDA-TiO2

    图  6  苯酮类小分子防晒剂与PDA-TiO2在(左)光学显微镜和(右)荧光显微镜下的皮肤渗透性

    Figure  6.  Skin permeability of benzophenone small molecule sunscreen and PDA-TiO2 under (left) optical microscope and (right) fluorescence microscope

    表  1  防晒霜的配方

    Table  1.   Formulation of sunscreen

    PhaseNamew/%
    Oil phaseOctadecanol3.0
    Beewax1.0
    Simethicone1.5
    Mono-fatty acid glycerides3.5
    Stearyl alcohol polyether-2/213.0
    Water phaseGlycerinum3.0
    Kalam-9400.3
    PDA-TiO25~25
    下载: 导出CSV

    表  2  掺入PDA-TiO2防晒霜的SPF

    Table  2.   SPF value of sunscreen with PDA-TiO2

    SampleSPF
    w(PDA-TiO2)=5%w(PDA-TiO2)=10%w(PDA-TiO2)=15%w(PDA-TiO2)=25%
    PDA-TiO2(1/10)8.2±1.312.3±1.221.4±2.533.7±2.9
    PDA-TiO2(1/20)4.2±1.16.6±1.713.5±1.821.2±3.2
    PDA-TiO2(1/30))2.6±0.94.8±1.310.2±2.314.6±2.1
    下载: 导出CSV
  • [1] GU Y, HAN J, JIANG C, et al. Biomarkers, oxidative stress and autophagy in skin aging [J]. Ageing Research Reviews,2020,59:101036. doi: 10.1016/j.arr.2020.101036
    [2] ERHAED H, HERBERT H. UV-radiation-sources, wavelength, environment [J]. Journal der Deutschen Dermatologischen Gesellschaft,2005,3 (Suppl 2):S3-S10.
    [3] SURJADINATA B, JACOBO D, CISNEROS L. UVA, UVB and UVC light enhances the biosynthesis of phenolic antioxidants in fresh-cut carrot through a synergistic effect with wounding [J]. Molecules,2017,22(4):668-681. doi: 10.3390/molecules22040668
    [4] HERRLING T, JUNG K, FUCHS J. The role of melanin as protector against free radicals in skin and its role as free radical indicator in hair [J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2008,69(5):1429-1435. doi: 10.1016/j.saa.2007.09.030
    [5] ZOU W, GONZALEZ A, JAMPAIAH D, et al. Skin color-specific and spectrally-selective naked-eye dosimetry of UVA, B and C radiations [J]. Nature Communications,2018,9(1):3743-3753. doi: 10.1038/s41467-018-06273-3
    [6] VELASCO M V R, SARRUF F D, SALGADO-SANTOS I M N, et al. Broad spectrum bioactive sunscreens [J]. International Journal of Pharmaceutics,2008,363(1-2):50-57. doi: 10.1016/j.ijpharm.2008.06.031
    [7] KULLAVANIJAYA P, LIM H W. Photoprotection [J]. Journal of the American Academy of Dermatology,2005,52(6):937-958. doi: 10.1016/j.jaad.2004.07.063
    [8] GARLAND C F, GARLAND F C, GORHAM E D. Could sunscreens increase melanoma risk? [J]. American Journal of Public Health,1992,82(4):614-625. doi: 10.2105/AJPH.82.4.614
    [9] WESTERDAHL J, INGVAR C, MASBCK A, et al. Sunscreen use and malignant melanoma [J]. International Journal of Cancer,2000,87(1):145-150. doi: 10.1002/1097-0215(20000701)87:1<145::AID-IJC22>3.0.CO;2-3
    [10] 曹妍, 骆丹. 防晒化妆品中的纳米技术 [J]. 中国美容医学杂志,2006,15(10):1206-1208.

    CAO Y, LUO D. Nanotechnology in sun-screening cosmetics [J]. Chinese Journal of Aesthetic Medicine,2006,15(10):1206-1208.
    [11] GIACOMONI P U, TETA L, NAJDEK L. Sunscreens: The impervious path from theory to practice [J]. Photochemical & Photobiological Sciences Official Journal of the European Photochemistry Association & the European Society for Photobiology,2010,9(4):524-529.
    [12] WU P, LEE Y, KUO Y, et al. Development of octyl methoxy cinnamates (OMC)/silicon dioxide (SiO2) nanoparticles by sol-gel emulsion method [J]. Nanomaterials,2017,7(12):434-444. doi: 10.3390/nano7120434
    [13] ZAYAT M, GARCIA-PAREGO P, LEVY D. Preventing UV-light damage of light sensitive materials using a highly protective UV-absorbing coating [J]. Chemical Society Reviews,2007,36(8):1270-1281. doi: 10.1039/b608888k
    [14] WANG Y, LI T, MA P, et al. Simultaneous enhancements of UV-shielding properties and photostability of poly(vinyl alcohol) via incorporation of sepia eumelanin [J]. ACS Sustainable Chemistry & Engineering,2016,4(4):2252-2258.
    [15] GOLLAVILLI H, HEGDE A R, MANAGULI R S, et al. Naringin nano-ethosomal novel sunscreen creams: Development and performance evaluation [J]. Colloids and Surfaces B: Biointerfaces,2020,193:111122-111134. doi: 10.1016/j.colsurfb.2020.111122
    [16] BANERJEE I, DE M, DEY G, et al. A peptide-modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model [J]. Biomaterials Science,2019,7(3):1161-1178. doi: 10.1039/C8BM01403E
    [17] 李晓燕, 刘志洪, 蔡汝秀. 黑色素对羟基自由基清除活性的研究 [J]. 四川大学学报(自然科学版),2003,40(6):1132-1136.

    LI X, LIU Z, CAI R. Study on scavenging activity of melanin to hydroxyl radical [J]. Journal of Sichuan University (Natural Science Edition),2003,40(6):1132-1136.
    [18] WANG L, DAI W, YANG M, et al. Cell membrane mimetic copolymer coated polydopamine nanoparticles for combined pH-sensitive drug release and near-infrared photothermal therapeutic [J]. Colloids and Surfaces B: Biointerfaces,2019,176:1-8. doi: 10.1016/j.colsurfb.2018.12.057
    [19] LEE S H, BAE I, LEE E, et al. Glucose exerts an anti-melanogenic effect by indirect inactivation of tyrosinase in melanocytes and a human skin equivalent [J]. International Journal of Molecular Sciences,2020,21(5):1736-1749. doi: 10.3390/ijms21051736
    [20] ROY S, VAN HAI L, KIM H C, et al. Preparation and characterization of synthetic melanin-like nanoparticles reinforced chitosan nanocomposite films [J]. Carbohydrate Polymers,2020,231:115729-115740. doi: 10.1016/j.carbpol.2019.115729
    [21] SEVER M J, WEISSER J T, MONAHAN J, et al. Metal-mediated cross-linking in the generation of a marine-mussel adhesive [J]. Angewandte Chemie International Edition,2004,43(4):448-450. doi: 10.1002/anie.200352759
    [22] 潘兵. 基于聚多巴胺的超疏水通用制备方法研究[D]. 江西: 南昌航空大学, 2014.

    PAN B. Universal strategies to fabricate superhydrophobic sufaces on different substrates based on polydopamine [D]. Jiangxi: Nanchang Hangkong University, 2014.
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出版历程
  • 收稿日期:  2021-01-04
  • 网络出版日期:  2021-03-05

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