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    冉海燕, 朱叶, 顾瑶, 罗静, 刘晓亚. 季铵化壳聚糖/纳米氧化锌杂化胶体粒子的制备及性能[J]. 功能高分子学报, 2020, 33(4): 390-398. doi: 10.14133/j.cnki.1008-9357.20190520001
    引用本文: 冉海燕, 朱叶, 顾瑶, 罗静, 刘晓亚. 季铵化壳聚糖/纳米氧化锌杂化胶体粒子的制备及性能[J]. 功能高分子学报, 2020, 33(4): 390-398. doi: 10.14133/j.cnki.1008-9357.20190520001
    RAN Haiyan, ZHU Ye, GU Yao, LUO Jing, LIU Xiaoya. Preparation and Properties of Quaternized Chitosan/Nano-Zinc Oxide Hybrid Colloidal Particles[J]. Journal of Functional Polymers, 2020, 33(4): 390-398. doi: 10.14133/j.cnki.1008-9357.20190520001
    Citation: RAN Haiyan, ZHU Ye, GU Yao, LUO Jing, LIU Xiaoya. Preparation and Properties of Quaternized Chitosan/Nano-Zinc Oxide Hybrid Colloidal Particles[J]. Journal of Functional Polymers, 2020, 33(4): 390-398. doi: 10.14133/j.cnki.1008-9357.20190520001

    季铵化壳聚糖/纳米氧化锌杂化胶体粒子的制备及性能

    Preparation and Properties of Quaternized Chitosan/Nano-Zinc Oxide Hybrid Colloidal Particles

    • 摘要: 以羟丙基三甲基氯化铵壳聚糖(QAC)和L-半胱氨酸(L-cys)为稳定剂制备羟丙基三甲基氯化铵壳聚糖/纳米氧化锌(QAC/ZnO)杂化胶体粒子。通过红外光谱、X射线衍射、X射线光电子能谱、热重分析对QAC/ZnO杂化胶体粒子的化学组成进行分析;用Zeta电位仪、纳米粒度仪、透射电镜对杂化胶体粒子的粒径及形貌进行了系统的表征;通过紫外、细胞实验等对杂化胶体粒子的紫外透光率、抗氧化性、光催化活性以及细胞毒性进行了表征。结果表明,QAC/ZnO杂化胶体粒子具有良好的紫外线屏蔽性和抗氧化性,且无细胞毒性,在防晒化妆品领域有一定的应用前景。

       

      Abstract: Quaternized chitosan/nano-zinc oxide (QAC/ZnO) hybrid colloidal particles were prepared by the self-assembly of quaternized chitosan (QAC), L-cysteine (L-cys) and the precursor of nano-zinc oxide Zn(CH3COO)2·2H2O. The chemical composition of QAC/ZnO hybrid colloidal particles was determined by Fourier transform-infrared spectroscopy (FT-IR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and thermogravimetic analysis(TG). The morphology and particle size of the hybrid colloidal particles were investigated in detail by means of Zeta potential analyzer, nanoparticle size analyzer and transmission electron microscopy (TEM). The ultraviolet transmittance, oxidation resistance, photocatalytic activity and cytotoxicity of the hybrid colloidal particles were studied by UV-Vis spectroscopy and the in vitro cell experiments. The results show that spherical QAC/ZnO hybrid colloidal particles can be successfully prepared by the self-assembly of QAC, L-cys and the precursor of nano-zinc oxide, and the size of the hybrid colloidal particles can be controlled by the concentration of nano-zinc oxide precursor. QAC/ZnO hybrid colloidal particles have good ultraviolet shielding property, excellent antioxidant property and low cytotoxicity. Moreover, the photocatalytic activity of the QAC/ZnO hybrid colloidal particles are significantly reduced in comparison with ZnO. It is expected to be used in cosmetics as an ultraviolet absorbent.

       

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