抗凝血生物材料的合成研究 Ⅴ．聚醚氨酯表面肝素化的新途径
Synthetic Studies on Blood Compatible Biomaterials V. A New Way for Surface Heparinization of Copolymer of Poly (ether urethane)
-
摘要: 本文报道聚醚氨酯表面肝素化的新途径：用聚醚氨酯预聚体、对一氯甲基苯乙烯、甲基丙烯酸甲酯三元共聚的方法，在聚氨酯链上导入活性氯甲基，氯甲基经三乙胺季控化后以离子键将肝素固定在共聚物表面。抗凝血初步试验表明，该途径相当有效。Abstract: A novel segmented polyurethane which was prepared from copolymerization of polyether-urethane,-chloromethylstyrene and methylmathacrylate has been heperinized on its surface. In this pecedure,triethylamine was first reacted with active chloromethyl group
下载: