壳聚糖基载药纳米微粒制备研究进展

Research Progress in the Preparation of Drug-loaded Nanoparticles Derived from Chitosan

摘要: 有关可生物降解多糖类纳米微粒用作给药载体的研究，近年颇受重视。简要评述了壳聚糖基载药纳米微粒的制备方法，包括共价交联、离子诱导、沉淀析出、大分子复合和自组装方法及其研究进展。

Abstract: Biodegradable polysaccharide-based nanoparticles are of increasing interest in recent years. The research progress in the preparation of chitosan-based nanoparticles as drug carriers were briefly reviewed, including covalently crosslinking, ionically indu