Abstract: The random copolymers based on methacrylate-hydroxyethyl methacrylate-poly(glycol) (MAA-HEMA-APEG) were synthesized by free radical solution polymerization.Then,using methoxysilane ether(KH560) as crosslinking agent,the anti-fog coatings were obtained by subsequent crosslinking reaction of the copolymers.The structures and thermal behaviors of the copolymers were characterized by means of Fourier Transform Infrared (FT-IR) spectroscopy,Nuclear Magnetic Resonance (¹H-NMR) spectrum and Differential Scanning Calorimetry (DSC).The contact angle,water resistance,light transmittance and anti-fog performance of the coatings were also evaluated.Results show that when the n(MAA):n(HEMA):n(APEG)=2:8:0.1 and the mass fraction of KH560 is 5%,the coating has excellent hydrophilicity and water swelling resistance.Moreover,the light transmittance of the material is hardly affected.