Abstract:
The composite microcapsules of PCL(polycaprolactone)-egg white were prepared via coaxial electrospraying.Egg white and PCL were used as the templates of protein drugs and drug carrier, respectively. The influence of solution properties, such as the conductivity and viscosity, to the final structure of the microspheres were investigated, as well as the influence of the operation parameters, including the ratio of the two liquid flow rates, voltage, collecting distance, etc, to the morphology of the microspheres. The products were characterized by optical microscope, SEM and Fluorescence microscope. Results show that the composite microcapsules of PCL-egg white can be prepared by coaxial electrospraying and the most outstanding affective parameter is the feeding ratio(γ) of PCL to egg white. Coated microspheres were obtained while γ is more than 10.