基于两步沉淀聚合法制备功能性聚苯乙烯微球

Preparation of Functional Polystyrene Microspheres Based on Two-Stage Precipitation Polymerization

摘要: 采用两步沉淀聚合法制备了带有原子转移自由基聚合(ATRP)引发基团的聚(苯乙烯-co-二乙烯苯)(P(St-co-DVB))微球，然后通过对P(St-co-DVB)微球进行表面引发ATRP接枝聚甲基丙烯酸二甲氨基乙酯(PDMAEMA)制备(P(St-co-DVB)-g-PDMAEMA)功能性聚合物微球。最后将P(St-co-DVB)-g-PDMAEMA微球进行季铵化反应。采用SEM、FT-IR、XPS对功能性微球形貌和结构进行表征。结果表明:制备的功能性微球粒径分布均一且表面光滑，平均直径为2.11 μm，季铵化之后的微球对大肠杆菌有很好的抑制作用。

Abstract: Poly (styrene-co-divinylbenzene) (P(St-co-DVB)) microspheres with atom transfer radical poly-merization (ATRP) initiator groups were prepared via two-stage precipitation polymerization. Then, poly (styrene-co-divinylbenzene) (P(St-co-DVB)) grafted poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA) (P(St-co-DVB)-g-PDMAEMA) microspheres were prepared via surface-initiated ATRP. Finally, the P(St-co-DVB)-g-PDMAEMA microspheres were conducted quaternization reaction. The morphologies and structures of microspheres were characterized by SEM, FT-IR and XPS. Results showed that the functional microspheres were featured by uniform size distribution and smooth surface, and the average particle size of microspheres was 2.11 μm. The bactericidal effect of microspheres on Escherichia coli was demonstrated.