异丙基丙烯酰胺))半互穿网络水凝胶的制备及其溶胀性能

Preparation and Swelling Properties of CrossLinked Poly(N-isopropylacrylamide)/(Sodium Alginate/Poly(N-isopropylacrylamide)) Semi-interpenetrating Polymer Network Hydrogel

摘要: 将线性聚(N-异丙基丙烯酰胺)（PNIPAAm）和海藻酸钠（SA）分子同时引入到PNIPAAm凝胶中，制备了交联聚(N-异丙基丙烯酰胺)/(海藻酸钠/聚(N异丙基丙烯酰胺))半互穿网络（Cr-PNIPAAm/(SA/PNIPAAm) semi-IPN）水凝胶。在弱碱性条件下(pH=7.4)，改变SA与线性PNIPAAm的质量比对Cr-PNIPAAm/(SA/PNIPAAm) semi-IPN水凝胶的溶胀度没有太大的影响。在酸性条件下(pH=1.0)，其溶胀度随着SA与线性PNIPAAm质量比的减小而增大。由于亲水性SA与线性PNIPAAm的协同作用，CrPNIPAAm/(SA/PNIPAAm) semi-IPN水凝胶的消溶胀速率得到很大提高。

Abstract: Cross-linked poly(N-isopropylacrylamide)/sodium alginate/linear poly(N-isopropylacrylamide) semi-interpenetrating polymer network (Cr-PNIPAAm/(SA/PNIPAAm) semi-IPN) hydrogels were prepared by addition of sodium alginate and linear PNIPAAm into cross-linked PNIPAAm hydrogel network. Results indicate that the mass ratios of SA to linear PNIPAAm have little effects on the swelling ratios of Cr-PNIPAAm/(SA/PNIPAAm) semi-IPN hydrogels in weakly alkaline medium (pH=7.4). Whereas the swelling ratios of the hydrogels increase with the reduce of the mass ratios of SA to linear PNIPAAm in strong acidic medium (pH=1.0). Compared with PNIPAAm hydrogels, the deswelling rates of CrPNIPAAm/(SA/PNIPAAm) semiIPN hydrogels are greatly enhanced due to the concurrent effect of the linear PNIPAAm and hydrophilic SA.