偶氮聚合物作为结肠靶向药物载体的研究进展

陈清元, 沈家瑞, 等. 偶氮聚合物作为结肠靶向药物载体的研究进展[J]. 功能高分子学报, 2001, 14(2): 252-256.

引用本文:

陈清元, 沈家瑞, 等. 偶氮聚合物作为结肠靶向药物载体的研究进展[J]. 功能高分子学报, 2001, 14(2): 252-256.

Studies of Azo-polymers for Colon-specific Drug Delivery[J]. Journal of Functional Polymers, 2001, 14(2): 252-256.

Citation:

Studies of Azo-polymers for Colon-specific Drug Delivery[J]. Journal of Functional Polymers, 2001, 14(2): 252-256.

Studies of Azo-polymers for Colon-specific Drug Delivery

摘要: 在人体消化道中，偶氮键仅能被结肠厌氧菌代谢的偶氮还原酶还原在耐断裂，偶氮聚合物可作为潜在的高定位性的结肠靶向药物缓释载体，根据合成方法和最终的释药方式，偶氮聚合物药物释放体系可分为水凝胶体系，胞衣体系和聚合物前药体系。

Abstract: In this article , a review of research in the colon specific drug delivery based on azo polymers in which azo groups are located in the main chain, cross links, or in branches, is given.

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