壳聚糖微球用于LHRH拮抗剂类似物缓释体系的研究
The Adsorption and Desorption of Chitosan Microspheres for LH-RH Antagonist
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摘要: 研究壳聚糖微球对促黄体生成激素释放激素(LHRH)拮抗剂类似物(TX46)的吸附与释放,考察了影响吸附与释放的因素,得到了各种不同微球对TX46的吸附与释放平衡曲线,为LHRH拮抗剂用于生育控制及其它临床应用提供了初步的实验依据。Abstract: The chitosan microspheres have been synthesized and used as LH-RH antagonist TX46 drug adsorbents. The mechanisms of the drug adsorption for LH-RH antagonist TX46 were investigated. The release experiment of the drug loaded on chitosan microspheres testif